CELL DIVISION

the process by which the nucleus of a cell divides, producing two nuclei with the diploid (2n--2 sets of chromosomes) number of chromosomes

I. INTERPHASE

* in between actual divisions
* the cell grows
* DNA exists as chromatin (a messy plate of spaghetti)
* the DNA duplicates (replicates) so now there are briefly 4 sets (4n); normally there are just 2 (2n)--one from each parent
* the centrioles also replicate (duplicate)

II. PROPHASE

* the DNA starts to condense and form chromosomes--the two halves of the chromosome (each chromatid) are held together at the centromere
* the nuclear membrane that keeps the DNA (now in the form of chromosomes) in the nucleus starts to disappear
* the centrioles start to move towards different ends (or poles) of the cell
* the spindle apparatus (looks like a cage) forms from the framework of the cell around the centrioles (which now are look like stars called 'asters')


III. METAPHASE

* the spindle apparatus is fully formed and the chromosomes attach to it at the centromere
* the chromosomes line up in the middle of the spindle (called the metaphase plate)

IV. ANAPHASE

* the chromosomes separate at the centromere and split apart (chromosomes move away from each other)
* the spindle fibers shorten and pull the chromosomes to each end (aster)

V. TELOPHASE

* the chromosomes have finished moving to the different poles (ends) of the cell
* a new nuclear membrane starts to form around each new COMPLETE set of chromosomes
* the DNA starts to uncoil again to form chromatin


AT THIS POINT, ONLY THE NUCLEUS HAS DIVIDED INTO 2 IDENTICAL NUCLEI...WE STILL HAVE ONLY 1 CELL!

VI. CYTOPLASMIC DIVISION

* after the reformation of the nuclear membrane, the cytoplasm divides
* this make 2 daughter cells that are identical to the parent, but smaller!


Mitosis and Asexual Reproduction

watch all the basics of mitosis
work with cells in different phases of mitosis
made for Regents biology, this is a must see animation/ description of mitosis
another John Kyrk animation, this time, of the process of mitosis
good review of the phases of the cell cycle; a couple of decent mitosis animations
a basic interactive animation of mitosis
fantastic interactive animation of the phases of mitosis